|Note: Definitions are expressed in terms applicable to the subjects of drug testing and pharmacology. Some terms maypossess inherently different meanings when applied to other fields of study.|
|Accuracy: The ability of a test device to produce a reading that matches the known value for the sample.|
|Amnestic: An agent used for the treatment of impaired memory function.|
|Analgesic: An agent that relieves pain selectively without affecting consciousness or sensory perception.|
|Anesthetic (General): An agent that produces unconsciousness as well as diminishing or eliminating the sensation of pain.|
|Anesthetic (Local): An agent that diminishes or eliminates the sensation of pain on or in the specific region of the body where it is applied.|
|Antihyperbilirubinemic: An agent used for the treatment of antihyperbilirubinemia (jaundice) - a common disorder in newborns wherein the chemical "bilirubin" accumulates in the infant's blood and causes a yellow hue.|
|Antitussive: An agent that suppresses coughing.|
|Anxiolytic: A mild sedative used for relief of anxiety.|
|Cannabinoid: Any of the active principles of Cannabis Sativa (marijuana), including, but not limited to, THC.|
|Central Nervous System (CNS): Body system comprised of the brain and spinal cord.|
|Central Nervous System (CNS) Depressant: An agent that diminishes brain and/or spinal cord function or activity.|
|Central Nervous System (CNS) Stimulant: An agent that amplifies brain and/or spinal cord function or activity.|
|Cross-reactivity: The degree in which substances other than the target compound are shown to generate positive test results.|
|Cutoff Concentration: The specific concentration of drug or drug metabolite in the sample that is chosen as a limit to distinguish a positive from a negative test result. Samples with concentrations above the cutoff level are considered positive and results below are considered negative.|
|Depressant: An agent that diminishes a body function or activity.|
|False Negative Test Result: A test result which states that no drug is present when, in fact, a tested drug or metabolite is present in an amount greater the cutoff concentration.|
|False Positive Test Result: A test result which states that a drug or metabolite is present when, in fact, the drug or metabolite is not present or is present in an amount less than the cutoff concentration.|
|Hallucinogen: An agent that distorts sensory perceptions, sometimes resulting in sensory illusions which may be mild or extreme.|
|Hypnotic: An agent that induces sleep.|
|Interference: The effect that a compound (or group of compounds) has on the accuracy of test measurement.|
|Metabolite: A modified form or byproduct of a drug produced by the body's metabolic process.|
|Narcotic (Narcotic-Analgesic): An agent that relieves pain through depression of the central nervous system.|
|Negative Test Result: A test result which states that no drug or metabolite is present or no drug or metabolite is present in an amount greater the cutoff concentration.|
|Positive Test Result: A test result which states that a drug or metabolite is present.|
|Precision: The ability of a test device to produce the same value during repeated measurements.|
|Quantitative Test Result: A test result expressed in numerical terms in order to determine the specific quantity of drug or drug metabolite present in the sample.|
|Qualitative Test Result: A test result expressed in non-numerical terms in order to determine the presence or absence of drug or drug metabolite in the sample.|
|Reproducibility: The ability of a test device to produce the same value during repeated measurements in various laboratories which are participating in a collaborative study.|
|Sedative: An agent that calms nervousness, irritability, and excitement. In general, sedatives depress the central nervous system and tend to cause sluggishness and reduced mental activity.|
|Sedative-Hypnotic: An agent that calms nervousness, irritability, and excitement and/or induces sleep. In general, sedative-hypnotics depress the central nervous system and tend to cause sluggishness and reduced mental activity.|
|Sensitivity: For quantitative test devices: The smallest concentration of a drug or drug metabolite that produces a response distinguishable from the background or blank value. For qualitative test devices: The minimum concentration of a drug or drug metabolite that is capable of generating a positive test result. In qualitative test devices, this amount is generally the same as the cutoff concentration.|
|Specificity: The ability of a test device to determine exclusively the drug and/or drug metabolites that are claimed to be detected without cross-reacting with other related substances that are not intended to be detected.|
|Stimulant: An agent that amplifies a body function or activity.|
|Target Drug/Metabolite: The drug or metabolite that the test device is designed to detect.|
|Tranquilizer: An agent used for relief of anxiety.
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